KMID : 0861020160310050107
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Korea Journal of Herbology 2016 Volume.31 No. 5 p.107 ~ p.114
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Antioxidant effect of ethanol extract from Poria cocos depending on cultivation methods
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Kim Yoo-Jin
Park Hae-Jin Lee Jin-Sang Do Eun-Ju Sohn Hyoung-Rac Jeon Seon-Man Yeum Jeong-Hyun Kim Mi-Ryeo
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Abstract
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Objectives : Poria cocos Wolf has been widely used in Korean medicine as a medicinal fungus. In this study, we investigated that comparative anti-oxidant effects of ethanol extract from wild Poria cocos (WP) and plastic bag-cultivated Poria cocos (PBP).
Methods : Total polyphenol and flavonoid contents in WP and PBP extract were monitored. And DPPH, ABTS, hydroxyl (¡¤OH) free radical scavenging capacity, reducing power and xanthine oxidase inhibition activities of them were determined at 5, 1, 0.5 mg/ml concentrations.
Results : Higher total polyphenol contents were found in the PBP extract (52.07¡¾0.6 mg/TAEg) than in the WP extract (28.44¡¾0.26 mg/TAEg). The flavonoid contents in WP and PBP extract were 17.29¡¾0.30 mg/ RUEg, 21.36¡¾0.40 mg/ RUEg, respectively. Also, DPPH, ABTS and ¡¤OH free radical scavenging capacity of PBP extract in treated concentrations (5, 1, 0.5 mg/ml) significantly increased compared to those of WP-treated group. In particular, DPPH, ABTS free radical scavenging capacity and reducing power of PBP extract at 5 mg/ml concentration were similar to positive control (BHA or vit. C). Xanthine oxidase (XO) inhibition rate in both extract increased dose dependently. But it was significantly increased in PBP-treated group, only at 5 mg/ml, compared to those of WP-treated group. Then, their inhibition rate by PBP was similar to positive control (BHA).
Conclusions : These results suggest that PBP extract is superior to WP extract in anti-oxidant capacity thus PBP can be applied in variable antioxidative products as a substitute for WP.
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KEYWORD
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Anti-oxidant, wild Poria cocos , plastic bag-cultivated Poria cocos , free radical scavenging capacity, total polyphenols
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